Inverse of Single Trait Additive Genetic Covariance Matrix with Unequal Variances Across Additive Genetic Groups

Estimating Additive and Non-Additive Genetic Variances and Predicting Genetic Merits Using Genome-Wide Dense Single Nucleotide Polymorphism Markers

Non-additive genetic variation is usually ignored when genome-wide markers are used to study the genetic architecture and genomic prediction of complex traits in human, wild life, model organisms or farm animals. However, non-additive genetic effects may have an important contribution to total genetic variation of complex traits. This study presented a genomic BLUP model including additive and ...

Effect of genetic groups on estimates of additive genetic variance.

This study examined the effect of genetic grouping on REML estimates of additive genetic variance with an animal model with selected base populations. A simulated population of 40 animals (20 males and 20 females) was followed under selection or random mating conditions for 10 generations. Each population was replicated 20 or 50 times. Genetic grouping reduced estimates of additive genetic vari...

Predictive Ability of Statistical Genomic Prediction Methods When Underlying Genetic Architecture of Trait Is Purely Additive

A simulation study was conducted to address the issue of how purely additive (simple) genetic architecture might impact on the efficacy of parametric and non-parametric genomic prediction methods. For this purpose, we simulated a trait with narrow sense heritability h2= 0.3, with only additive genetic effects for 300 loci in order to compare the predictive ability of 14 more practically used ge...

Genome-Enabled Estimates of Additive and Nonadditive Genetic Variances and Prediction of Apple Phenotypes Across Environments

The nonadditive genetic effects may have an important contribution to total genetic variation of phenotypes, so estimates of both the additive and nonadditive effects are desirable for breeding and selection purposes. Our main objectives were to: estimate additive, dominance and epistatic variances of apple (Malus × domestica Borkh.) phenotypes using relationship matrices constructed from genom...

Additive Genetic Variance